Some observations on mixtures of serum albumin and globulin

Abstract

Measurements of ultra violet absorption spectra, potentiometric titration curves and precipitability by ammonium sulphate made on mixed solns. of serum proteins showed no anomalous mixture effects; osmotic pressures of mixtures were greater than those expected from osmotic pressures of the separate components. The bearing of these results on those of McFarlane [see B. A. 9(9): Entry 18247] and of Pedersen [see B. A. 11(4): Entry 8072] obtained with the ultra centrifuge was discussed. No known hypothesis could account for all these observations.