The effect of sequence quality on sequence alignment
Open Access
- 23 February 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 24 (7), 897-900
- https://doi.org/10.1093/bioinformatics/btn052
Abstract
Motivation: The nucleotide sequencing process produces not only the sequence of nucleotides, but also associated quality values. Quality values provide valuable information, but are primarily used only for trimming sequences and generally ignored in subsequent analyses.Keywords
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