Some aspects of the pharmacology of ibufenac, a non-steroidal anti-inflammatory agent
- 12 April 1968
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 20 (4), 305-312
- https://doi.org/10.1111/j.2042-7158.1968.tb09744.x
Abstract
When given orally to animals ibufenac has a range of potencies 2 to 4 times that of aspirin. It also suppresses thurfyl nicotinate erythema in man. Like certain other analgesic-anti-inflammatory-antipyretic drugs, when administered intravenously it suppresses bradykinin-induced bronchoconstriction in the guinea-pig. It has no glucocorticoid activity. Ibufenac, a compound chemically unrelated to existing antirheumatic drugs, can thus be classified as a non-steroidal anti-inflammatory (antirheumatic) agent.This publication has 13 references indexed in Scilit:
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