IN CERTAIN circumstances, vascular access for chronic intravenous chemotherapy in patients with malignant disease becomes difficult. Suitable superficial veins for the administration of chemotherapy occasionally become unavailable during the course of a prolonged regimen. The following case report illustrates an instance when a bovine heterograft arteriovenous fistula was used for repetitive chemotherapy in a patient with Hodgkin disease. Report of a Case A problem was recently encountered in finding venipuncture sites for the administration of intravenous medication to a 22-year-old girl suffering from nodular sclerosing Hodgkin disease. An attempt was made to administer chemotherapy, but superficial veins were impossible to find. It was decided to create a bovine graft arteriovenous fistula so that combination intravenous medication could be administered and the necessary blood samples for analysis drawn. On May 6,1974, a bovine heterograft arteriovenous fistula was created as a loop in her left arm. A 6.5-mm bovine graft was anastomosed