Comparison of beta-galactosidases from normal (i-o+z+) and operator constitutive (i-ocz+) strains of E. coli.

Abstract
The properties of purified [beta]-galactosidases from a normal constitutive strain of E. coli K12 (3300, i-o+z+) and from an operator constitutive mutant (o6 c 7, i-ocz+) have been compared using physical, chemical, and biological methods. No detectable differences were found between the two protein preparations. It is concluded that the operator locus does not specify any part of the structure of the [beta]-galactosidase molecule.