Mass spectrometric studies of twenty-one metabolically important acylglycines

Abstract

The mass spectra of the methyl esters of twenty‐one metabolically important N‐acylglycines are reported. The spectra are discussed in terms of their fragmentations and their application to studies of metabolic diseases. In particular, the high relative abundance of the peak at m/e 30 in the spectra of many aliphatic acylglycine methyl esters was studied by using ([2,2‐²H₂]propionyl)glycine and high resolution mass spectrometry. This fragment was assigned to the even‐electron ion [CH₂ = NH₂]⁺.