The third allele of supernatant isocitrate dehydrogenase of house mouse, iId-1c, originates from asian continent.

Abstract

Electrophoretic survey of Id-1 alleles in the Japanese wild mouse, Mus musculus molossinus, revealed the existence of 4 alleles, Id-1a, Id-1b, Id-1c and Id-1d. Two alleles, Id-1c and Id-1d, are not present in European and American wild mouse populations and had overall frequencies of 0.138 and 0.006, respectively, in the Japanese mouse. The Id-1b allele was most frequent (0.782) and the Id-1a was relatively rare (0.074). Geographically, the northern populations possess mostly Id-1b alleles (0.985), while Id-1a, Id-1b and Id-1c alleles are common in the southern regions. This geographical distribution can be explained by the multiple migration hypothesis of the wild mouse into Japan through 2 southern routes. This explanation is partly supported by the presence of the Id-1c allele in the Asian house mouse from the Philippines and Thailand.