Modification of the kinetic parameters of aldolase on binding to the actin-containing filaments of skeletal muscle

Abstract
The kinetic parameters of [ox] fructose bisphosphate aldolase (EC 4.1.2.13) were apparently modified on binding of the enzyme to the actin-containing filaments of skeletal muscle. Although binding to F-actin or F-actin-tropomyosin filaments resulted in relative minor changes in kinetic properties, binding to F-actin-tropomyosin-troponin filaments produced major alterations in the kinetic parameters and renders them Ca2+-sensitive.