Slow-Reacting Substance of Anaphylaxis: Studies on Purification and Characterisation
- 1 January 1979
- book chapter
- Published by Springer Nature
- No. 6,p. 27-36
- https://doi.org/10.1007/978-3-0348-7232-4_3
Abstract
We have demonstrated the role of arachidonic acid and lipoxygenase in the genesis of SRS-A and the possible role of lipoxygenases in its metabolism. SRS-A has been purified in microgram quantities together with closely related material. We have identified 5,12 di-hydroxy-6, 8, 10, 14 eicosatetranenoic acid released by antigen challenge, and which we feel is related to SRS-A. Further structural work is in progress.Keywords
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