An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Top Cited Papers
- 1 June 2006
- Vol. 125 (6), 1137-1149
- https://doi.org/10.1016/j.cell.2006.05.013
Abstract
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This publication has 42 references indexed in Scilit:
- A Src-Like Inactive Conformation in the Abl Tyrosine Kinase DomainPLoS Biology, 2006
- Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancersInternational Journal of Cancer, 2006
- EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinibProceedings of the National Academy of Sciences, 2004
- EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib TherapyScience, 2004
- Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to GefitinibNew England Journal of Medicine, 2004
- EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain DimerizationMolecular Cell, 2003
- Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular DomainsCell, 2002
- Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor αCell, 2002
- Structure of the Extracellular Region of HER3 Reveals an Interdomain TetherScience, 2002
- Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain11Edited by B. HollandJournal of Molecular Biology, 2001