α-1-Anti-trypsin, an inhibitor of renin
- 1 February 1976
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 153 (2), 505-507
- https://doi.org/10.1042/bj1530505
Abstract
A naturally occurring competitive inhibitor of pig kidney renin has been identified in human plasma. The inhibitor was shown to be α-1 anti-trypsin and the effect in vitro on the renin activity was examined. The slope in the Hill plot is compatible with the assumption of one-site competitive inhibition. Other proteinase inhibitors, such as α-2-macroglobulin and C1 inactivator, however, have no inhibitory effect on the renin-angiotensinogen reaction.This publication has 12 references indexed in Scilit:
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