Brain uptake of ketoprofen–lysine prodrug in rats
- 19 August 2010
- journal article
- Published by Elsevier BV in International Journal of Pharmaceutics
- Vol. 399 (1-2), 121-128
- https://doi.org/10.1016/j.ijpharm.2010.08.019
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?Nature Reviews Drug Discovery, 2008
- On The Rate and Extent of Drug Delivery to the BrainPharmaceutical Research, 2007
- Challenges for blood–brain barrier (BBB) screeningXenobiotica, 2007
- Central Nervous System Drug Disposition: The Relationship between in Situ Brain Permeability and Brain Free FractionJournal of Pharmacology and Experimental Therapeutics, 2007
- Targeting the Cerebrovascular Large Neutral Amino Acid Transporter (LAT1) Isoform Using a Novel Disulfide-Based Brain Drug Delivery SystemDrug Delivery, 2007
- Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and BrainJournal of Pharmacology and Experimental Therapeutics, 2005
- Considerations in the Use of Cerebrospinal Fluid Pharmacokinetics to Predict Brain Target Concentrations in the Clinical SettingClinical Pharmacokinetics, 2002
- Conjugation with L-Glutamate forin vivoBrain Drug DeliveryJournal of Drug Targeting, 2001
- Human LAT1, a Subunit of System L Amino Acid Transporter: Molecular Cloning and Transport FunctionBiochemical and Biophysical Research Communications, 1999
- Transport of Gabapentin, a γ‐Amino Acid Drug, by System L α‐Amino Acid Transporters: A Comparative Study in Astrocytes, Synaptosomes, and CHO CellsJournal of Neurochemistry, 1995