Considerations in the Use of Cerebrospinal Fluid Pharmacokinetics to Predict Brain Target Concentrations in the Clinical Setting
Top Cited Papers
- 1 January 2002
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 41 (10), 691-703
- https://doi.org/10.2165/00003088-200241100-00001
Abstract
In the clinical setting, drug concentrations in cerebrospinal fluid (CSF) are sometimes used as a surrogate for drug concentrations at the target site within the brain. However, the brain consists of...Keywords
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