Cigarette Smoking and Human Pulmonary Macrophages
- 1 September 1977
- journal article
- research article
- Published by Taylor & Francis in Hospital Practice
- Vol. 12 (9), 97-104
- https://doi.org/10.1080/21548331.1977.11707193
Abstract
Bronchial lavage recovers about four times as many free cells, particularly pulmonary alveolar macrophages, from smokers as from nonsmokers. These cells display altered surface morphology, increased lysosomal enzymes, fewer complement receptors, decreased phagocytic activity against some bacteria, and unresponsiveness to migration inhibitory factor, possibly indicating a defect in cell-mediated immunity.Keywords
This publication has 5 references indexed in Scilit:
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- Altered Morphology and Increased Acid Hydrolase Content of Pulmonary Macrophages from Cigarette Smokers1–4American Review of Respiratory Disease, 1973
- The human alveolar macrophage: isolation, cultivation in vitro, and studies of morphologic and functional characteristicsJCI Insight, 1971
- Human alveolar macrophages: comparison of phagocytic ability, glucose utilization, and ultrastructure in smokers and nonsmokersJCI Insight, 1970
- Bronchopulmonary Lavage in Normal Subjects and Patients with Obstructive Lung DiseaseAnnals of Internal Medicine, 1967