Coexistence of renin and cathepsin B in epithelioid cell secretory granules
- 1 January 1985
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 83 (2), 103-108
- https://doi.org/10.1007/bf00495138
Abstract
Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin- and cathepsin B-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin B is suggested to be involved in the activation of renin prior to secretion.Keywords
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