A comparison of some gradient-encoded volume-selection techniques forin vivo NMR spectroscopy

Abstract

Four of the techniques proposed for in vivo volume‐selected NMR spectroscopy have been compared using a simple phantom with a large background water signal which was outside the region of interest. The methods VSE, SPACE, SPARS, and DIGGER all use pulsed field gradients for spatial encoding and were tested with a symmetric and an asymmetric phantom. SPACE was used to obtain volume‐selected ¹H NMR spectra of a human leg, demonstrating excellent discrimination between bone marrow and muscle. © 1987 Academic Press, Inc.