The neutralization of pox viruses I. Evidence for antibody interference
- 1 December 1968
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 66 (4), 541-548
- https://doi.org/10.1017/s002217240002828x
Abstract
Evidence was presented to support a hypothesis that competition between antibody molecules can be an important factor in vaccinia virus neutralization. It has been shown that there is little difference in the virus neutralizing properties of 7 S and 19 S antibody and it has been further postulated that in the context of protective immunity the proportions of antibodies having neutralizing and interfering effects is likely to be more important than the absolute concentration of neutralizing antibody or the type of immunoglobulin in which it is present.Keywords
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