Pressing and squeezing with Piezos
Open Access
- 5 November 2010
- journal article
- Published by Springer Nature in EMBO Reports
- Vol. 11 (12), 902-903
- https://doi.org/10.1038/embor.2010.181
Abstract
Our molecular understanding of somatosensation has been hampered by the difficulty in identifying the sensor in mammals. In a real breakthrough for the field, two proteins—Piezo 1 and 2—have recently been identified as the elusive mechano-sensors!Keywords
This publication has 12 references indexed in Scilit:
- Multiple Desensitization Mechanisms of Mechanotransducer Channels Shape Firing of Mechanosensory NeuronsJournal of Neuroscience, 2010
- Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation ChannelsScience, 2010
- Polycystins under PressureCell, 2009
- TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16AJournal of Biological Chemistry, 2009
- Mammalian somatosensory mechanotransductionCurrent Opinion in Neurobiology, 2009
- TRP channels in mechanosensation: direct or indirect activation?Nature Reviews Neuroscience, 2007
- Mechanisms of sensory transduction in the skinNature, 2007
- Symbol-intertextuality-deconstruction (on the dialectic of stability and variability of concept and symbol)Semiotica, 2007
- Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacologyToxicon, 2006
- A possible unifying principle for mechanosensationNature, 2005