Metacarpophalangeal pattern profile analysis in sotos syndrome: A follow‐up report on 34 subjects
- 1 January 1988
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 29 (1), 143-147
- https://doi.org/10.1002/ajmg.1320290118
Abstract
Metacarpophlangeal pattern profile (MCPP) was determined on 34 Sotos syndrome individuals and compared with previous MCPP studies. The mean hand profile contained a major peak in the proximal phalangeal area and a smaller peak in the metacarpal area, while the distal hand bones were relatively short. There appear to be three recognized hand profiles in Sotos syndrome, which suggests heterogeneity of the syndrome, although correlation studies indicate clinical homogeneity of individuals in the younger age groups. Discriminant analysis of Sotos syndrome versus control subjects produced a function of two MCPP variables, plus age, which may be applied as another diagnostic tool.Keywords
This publication has 7 references indexed in Scilit:
- Metacarpophalangeal pattern profile analysis in Sotos syndrome: An updateAmerican Journal of Medical Genetics, 1986
- Metacarpophalangeal pattern profile analysis in clinical genetics: An applied anthropometric methodAmerican Journal of Physical Anthropology, 1986
- Cerebral gigantism (Sotos syndrome) in two patients with fra(X) chromosomesAmerican Journal of Medical Genetics, 1986
- Zerebraler Gigantismus (Sonos-Syndrom)RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 1985
- Cerebral gigantism (Sotos syndrome). Compiled data of 22 casesEuropean Journal of Pediatrics, 1985
- Metacarpophalangeal pattern profile analysis in Sotos syndromeAmerican Journal of Medical Genetics, 1985
- Metacarpophalangeal Length in the Evaluation of Skeletal MalformationRadiology, 1972