On Some Histochemical Aspects of the Otosclerotic Focus: State and Significance of the Sulfhydril Groups

Abstract

The demonstration of sulfhydril groups in the region of the otospongious focus during the course of the first stages of their evolution seems to us to be of a twofold interest. They indicate a proteolytic activity in the region of the fundamental substance in the bone, and equally constitute a characteristic trait, in the histochemical field, of the first stages of the disease.