An adipogenic serum factor in genetically obese rodents
- 7 March 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 153 (1), 179-182
- https://doi.org/10.1016/0014-5793(83)80143-4
Abstract
The adipose conversion of 3T3-Li cells depends on a serum factor present in high amounts in fetal calf serum, which is heat stable and can be extracted from serum by ethanol precipitation. Sera of two genetically obese rodent species, fa/fa Zucker rats and C57Bl/KsJ-db/db mice, contain a high adipogenic activity which is very similar to that found in fetal calf serum. In contrast, sera of their lean siblings (Fa/Fa-Zucker rats and C57Bl/KsJ-+/+ mice) are devoid of adipogenic activity.Keywords
This publication has 18 references indexed in Scilit:
- Growth hormone and the adipose conversion of 3T3 cellsCell, 1982
- Formation of normally differentiated subcutaneous fat pads by an established preadipose cell lineJournal of Cellular Physiology, 1979
- Levels of Prolactin, Growth Hormone and Insulin in Genetically Diabetic (db/db) MiceExperimental Biology and Medicine, 1979
- Diurnal Changes in Serum Metabolites and Hormones in Lean and Obese Zucker RatsHormone and Metabolic Research, 1978
- THE ADIPOSE CONVERSION OF 3T3 CELLSPublished by Elsevier ,1978
- Serum Hormone Levels and Tissue Metabolism in Pair-Fed Lean and Obese Zucker RatsHormone and Metabolic Research, 1977
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- Spontaneous heritable changes leading to increased adipose conversion in 3T3 cellsCell, 1976
- An improved fluorometric assay for DNAAnalytical Biochemistry, 1971