Studies on Pyridazinone Derivatives. VII. Synthesis of Urinary Metabolites of 4-Ethoxy-2-methyl-5-morpholino-3 (2H)-pyridazinone (M73101) in Human

Abstract

Among 7 metabolites which were isolated from the urine of a man administered with 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (M-73101), 6 metabolites were synthesized. Chemical structure of the synthesized samples was confirmed by instrumental analysis and direct comparison with the metabolites.