White-Gray Matter Differentiation in Computed Tomography

Abstract
A numerical analysis has been performed on six regions of interest within the brain for a total of 60 patients. Three areas of white matter and three of gray matter were included. A difference of 7.1 ± 1.3 Hounsfield units (HU: 1.000 scale) was found between white and gray matter. For eight patients who were under 15 years of age. the difference was 5.1 ± 0.6 HU. Contrast injection resulted in a general increase of values, with gray matter showing a greater elevation by 0.5 HU. The numerical evaluation of white and gray matter has proven to be useful in the diagnosis of leukoencephalopathy.