SYNTHESIS AND RADIORECEPTOR BINDING ACTIVITY OF TURKEY β-ENDORPHIN AND DEACETYLATED SALMON ENDORPHIN
- 12 January 2009
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 16 (1), 75-78
- https://doi.org/10.1111/j.1399-3011.1980.tb02938.x
Abstract
Des-acetylated salmon endorphin and turkey .beta.-endorphin were synthesized by the solid-phase method. Relative opiate activities in a radioreceptor binding assay [rat brain] are: human .beta.-endorphin, 100; des-acetylated salmon endorphin, 169; turkey .beta.-endorphin, 94. Thus, non-mammalian endorphins can show high activity in a mammalian assay system.Keywords
This publication has 18 references indexed in Scilit:
- HUMAN SOMATOTROPINInternational Journal of Peptide and Protein Research, 2009
- β-Endorphin: Characteristics of binding sites in the rat brainBiochemical and Biophysical Research Communications, 1979
- Isolation and primary structure of endorphin from salmon pituitary glandsBiochemical and Biophysical Research Communications, 1979
- Isolation and primary structure of β-endorphin and β-lipotropin from bovine pituitary glandsBiochemical and Biophysical Research Communications, 1977
- Synthesis and analgesic activity of human .beta.-endorphinJournal of Medicinal Chemistry, 1977
- Isolation, characterization and opiate activity of β-endorphin from human pituitary glandsBiochemical and Biophysical Research Communications, 1976
- Opioid Peptides Endorphins in Pituitary and BrainScience, 1976
- Isolation of peptides with opiate activity from sheep and human pituitaries: Relationship to beta-lipotropinBiochemical and Biophysical Research Communications, 1976
- Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.Proceedings of the National Academy of Sciences, 1976
- Lipotropin: Precursor to two biologically active peptidesBiochemical and Biophysical Research Communications, 1976