Rheb Binds and Regulates the mTOR Kinase
Top Cited Papers
- 1 April 2005
- journal article
- research article
- Published by Elsevier in Current Biology
- Vol. 15 (8), 702-713
- https://doi.org/10.1016/j.cub.2005.02.053
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveNature Cell Biology, 2004
- Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP ActivityMolecular and Cellular Biology, 2004
- Identification of Dominant Negative Mutants of Rheb GTPase and Their Use to Implicate the Involvement of Human Rheb in the Activation of p70S6KJournal of Biological Chemistry, 2003
- Rheb is a direct target of the tuberous sclerosis tumour suppressor proteinsNature Cell Biology, 2003
- Rheb is an essential regulator of S6K in controlling cell growth in DrosophilaNature Cell Biology, 2003
- Two Motifs in the Translational Repressor PHAS-I Required for Efficient Phosphorylation by Mammalian Target of Rapamycin and for Recognition by RaptorJournal of Biological Chemistry, 2003
- TOR signalling in bugs, brain and brawnNature Reviews Molecular Cell Biology, 2003
- Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cellsOncogene, 2002
- mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth MachineryCell, 2002
- Phosphatidylinositol 4‐kinasesEuropean Journal of Biochemistry, 1998