THE RESPIRATORY AND CIRCULATORY RESPONSES TO INTRAVENOUS OXYGEN AND THEIR RELATION TO ANOXEMIA

Abstract

Temporary pulmonary embolism in dogs is produced by the intraven. introduction of O2. It is accompanied by anoxemia beginning almost immediately which is shown to be related to an increased pressure in the right ventricle. The aortic pressure, if the inj. is sufficiently slow, does not fall. The causes of this anoxemia are discussed. There is also a marked increase in pulmonary ventilation beginning somewhat later than the anoxemia and persisting long after it has disappeared. This is due to a reflex passing up the vagus and probably arising from the pulmonary circuit.