DNA Synthesis in Infectious Mononucleosis and Acute Leukaemia

Abstract

Combined autoradiographic and quantitative cytochemical studies have been made on leukocytes in leukemia and infectious mononucleosis. DNA synthesis in the majority of cells in both these diseases follows the same pattern. Some of the leukemic cells had abnormally high rates of DNA synthesis. There is evidence to suggest that arrest of DNA synthesis can occur in the replicating leukemic cells.