Multigene Family for Sarcomeric Myosin Heavy Chain in Mouse and Human DNA: Localization on a Single Chromosome
- 19 August 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4612), 766-769
- https://doi.org/10.1126/science.6879174
Abstract
Cloned myosin H chain DNA probes from rats and humans were hybridized to restriction endonuclease digests of genomic DNA from somatic cell hybrids and their parental cells. The mouse myosin H chain genes detectable by this assay were located on chromosome 11, and 3 different human sarcomeric myosin H chain genes were mapped to the short arm of chromosome 17. A synteny between myosin H chain and 2 unrelated markers, thymidine kinase and galactokinase, was found to be preserved in the rodent and human genomes.This publication has 29 references indexed in Scilit:
- Clustering of Leukocyte and Fibroblast Interferon Genes of Human Chromosome 9Science, 1982
- Structural genes of the mouse major urinary protein are on chromosome 4.The Journal of cell biology, 1982
- Organization of the constant-region gene family of the mouse immunoglobulin heavy chainCell, 1982
- Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.The Journal of Experimental Medicine, 1980
- Molecular cloning and characterization of the human β-like globin gene clusterCell, 1980
- Recent developments in the molecular genetics of human hemoglobinCell, 1979
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Glk: A locus controlling galactokinase activity in the mouseBiochemical Genetics, 1976
- Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology, 1975
- Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed RecombinantsScience, 1964