Synthèse énantiospécifique du (−)‐(1R, 3R, 5S)‐diméthyl‐1,3‐dioxa‐2,9‐bicyclo[3.3.1]nonane
- 20 September 1989
- journal article
- research article
- Published by Wiley in Helvetica Chimica Acta
- Vol. 72 (6), 1284-1287
- https://doi.org/10.1002/hlca.19890720615
Abstract
Enantiospecific Synthesis of (−)‐(1R, 3R, 5S)‐1,3‐Dimethyl‐2,9‐dioxabicyclo[3.3.1]nonaneThe isomer (−)‐(1R, 3R, 5S)‐endo‐1,3‐dimethyl‐2,9‐dioxabicyclo[3.3.1]nonane ((1R, 3R, 5S)‐8) has been synthesized from (−)‐(3R)‐methyl 3‐hydroxybutanoate. The key intermediate (3R, 5R)‐5 is proved to be a useful synthon for EPC syntheses.This publication has 9 references indexed in Scilit:
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