The Mechanism of Action of Multidrug-Resistance-Linked P-Glycoprotein
- 1 January 2001
- journal article
- review article
- Published by Springer Nature in Journal of Bioenergetics and Biomembranes
- Vol. 33 (6), 481-491
- https://doi.org/10.1023/a:1012875105006
Abstract
P-glycoprotein (Pgp), the ATP-binding cassette (ABC) transporter, confers multidrug resistance to cancer cells by extruding cytotoxic natural product amphipathic drugs using the energy of ATP...Keywords
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