STUDIES ON INFLUENZA INFECTION IN FERRETS BY MEANS OF FLUORESCEIN-LABELLED ANTIBODY
Open Access
- 1 June 1955
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 101 (6), 677-686
- https://doi.org/10.1084/jem.101.6.677
Abstract
Yellow-green fluorescence representing viral antigens was detected in both the nucleus and cytoplasm of epithelial cells of the respiratory tract in ferrets infected with influenza virus. This nuclear fluorescence was the chief manifestation of cross-fluorescent staining reactions among three strains of influenza A virus studied, PR8, Farrington, and Fm1. Absorption experiments with influenza viral V and soluble S antigens showed that S antigen was responsible for the presence of fluorescence in the nucleus and for the cross-staining reactions among these strains.Keywords
This publication has 8 references indexed in Scilit:
- STUDIES OF INFLUENZA VIRUS INFECTION IN THE CHICK EMBRYO USING FLUORESCENT ANTIBODYThe Journal of Experimental Medicine, 1954
- THE ANTIGENIC COMPOSITION OF INFLUENZA VIRUS MEASURED BY ANTIBODY-ABSORPTIONThe Journal of Experimental Medicine, 1953
- THE LOCALIZATION OF HOMOLGOUS PLASMA PROTEINS IN THE TISSUES OF YOUNG HUMAN BEINGS AS DEMONSTRATED WITH FLUORESCENT ANTIBODIESThe Journal of Experimental Medicine, 1953
- OBSERVATIONS WITH THE ELECTRON MICROSCOPE ON CELLS OF THE CHICK CHORIO-ALLANTOIC MEMBRANE INFECTED WITH INFLUENZA VIRUSThe Journal of Experimental Medicine, 1952
- LOCALIZATION OF ANTIGEN IN TISSUE CELLSThe Journal of Experimental Medicine, 1951
- The Intracellular Distribution in Rabbit Liver of Injected Antigens Labeled with I 131Science, 1950
- A Comparison of Influenza Complement Fixation Antigens Derived from Allantoic Fluids and MembranesThe Journal of Immunology, 1950
- STUDIES ON THE COMPLEMENT FIXATION ANTIGENS OF INFLUENZA VIRUSES TYPES A AND B.1946