Prostaglandins Cause An Increase in Serum Acute-Phase Proteins in Man, Which is Diminished in Systemic Sclerosis
- 1 February 1984
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 66 (2), 165-171
- https://doi.org/10.1042/cs0660165
Abstract
The prostaglandin E1 increases the plasma concentration of acute-phase proteins in man and decreases the concentration of certain carrier proteins. This response is greatly diminished in patients with systemic sclerosis, a chronic inflammatory disease leading to fibrosis. These findings pose new questions about the mediation of the acute-phase response and its role in controlling the inflammatory process.This publication has 4 references indexed in Scilit:
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