THE β-OXIDATIVE DEGRADATION OF DOCOSENOIC ACIDS TO EICOSENOIC AND OCTADECENOIC ACIDS IN THE RAT
- 30 June 1967
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 45 (7), 1075-1079
- https://doi.org/10.1139/o67-124
Abstract
Methyl esters of monoenoic acids from rat tissue lipids were prepared and isolated by silver nitrate – silicic acid column chromatography and further separated according to chain length by preparative gas–liquid chromatography. Each monoenoic fraction was then oxidized for subsequent gas–liquid chromatography to distinguish isomeric intermediates of β-oxidation.Cetoleic acid (11-docosenoic), an isomer of erucic acid (13-docosenoic), was dagraded by the rat to gadoleic (9-eicosenoic) and 7-octadecenoic acids. By analogy, dietary erucic acid would contribute to the content of 11-eicosenoic and oleic (9-octadecenoic) acids in the tissue lipids.This publication has 13 references indexed in Scilit:
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