Nitrate nitrogen levels in drinking water of urban areas with high- and low-risk populations for stomach cancer: an environmental epidemiology study
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Zeitschrift für Krebsforschung und Klinische Onkologie
- Vol. 92 (3), 227-234
- https://doi.org/10.1007/bf00461645
Abstract
A correlation study between mean nitrate nitrogen levels (ppm) in drinking water samples (N=1389) of Chilean urban areas and age-adjusted death rates per 100000 population from stomach cancer, by province or region and sex, was made. Drinking water samples from all provinces (N=25) had a weighed mean of 1.446 ppm (S.E.M. 0.068) with a range of 0.00–30.00 ppm. Nitrate nitrogen levels showed a positive but not significant association with male death rates. The correlation coefficient was +0.0335. Similarly, such levels did exhibit a positive but not significant correlation with female death rates (r=+0.0486). When NO3-N levels and male (r=+0.1367) or female (r=+0.1143) death rates were studied, by region, positive but insignificant correlations were detected. Using Cochran's approximation, mean nitrate nitrogen levels in drinking water samples from six provinces with 50% of the Chilean population (period 1953–55 versus 1973–75), showed a decrease from 1.835 to 1.291 ppm, but there was no significant difference (t=1.32) between the two values, except in samples from Santiago Province (t=2.11, P<0.05). Provinces (south central area) showing the highest gastric cancer mortality rates in the world for females (up to 40.8/100,000), and ranking second for males (up to 84.1/100,000), exhibited a very low mean level (0.825 ppm).Keywords
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