Specific alignment of nucleosomes on DNA correlates with periodic distribution of purine—pyrimidine and pyrimidine—purine dimers
Open Access
- 25 July 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 158 (2), 293-297
- https://doi.org/10.1016/0014-5793(83)80598-5
Abstract
Comparison of the X‐ray data and results of conformational analysis reveals the sequence‐dependent helical anisotropy of DNA: purine—pyrimidine (RY) and pyrmidine—purine (YR) dimers prefer bending in the opposite directions. On this basis it is suggested that in the optimal nucleosomal DNA sequence the RY and YR dinucleotides alternate at intervals of 5–6 basepairs. Examination of the cases with the known disposition of nucleosomes confirms this concept.Keywords
This publication has 24 references indexed in Scilit:
- Mechanics of sequence-dependent stacking of bases in B-DNAJournal of Molecular Biology, 1982
- The location of nucleosomes in chromatin: specific or statistical?Nature, 1981
- Structure of a B-DNA dodecamerJournal of Molecular Biology, 1981
- Face to phase with nucleosomesCell, 1981
- Chromatin structure of the histone genes of D. melanogasterCell, 1981
- Chromatin structure of the 5S RNA genes of D. melanogasterCell, 1980
- Nonrandom alignment of nucleosomes on 5S RNA genes of X. laevisCell, 1980
- The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase INature, 1980
- Primary organization of the nucleosome core particles sequential arrangement of histones along DNAJournal of Molecular Biology, 1980
- Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleasesCell, 1978