GRIMSON and his co-workers recently advocated in a preliminary report of four cases the successful use of a new anticholinergic drug, banthine® bromide (beta-diethylaminoethyl xanthene-9-carboxylate methobromide), in the treatment of hyperhidrosis.1 The purpose of this report is to describe the use of banthine® bromide not only in the treatment of hyperhidrosis but also in the treatment of several of the common dermatoses aggravated by or possibly produced by excessive sweating. Twenty-seven patients were divided into two groups. The first group of patients were those with functional disturbances of the sympathetic nervous system, characterized by localized hyperhidrosis involving the palms, soles, and axillae, alone or conjointly. This condition is usually symmetrical; the affected parts are cold and clammy to the touch, and the skin is frequently macerated, sodden, and thickened. REPORT OF CASES Mrs. E. P., a 40-yr.-old housewife, had complained of hyperhidrosis for 15 yr. This condition was present