Atomic Resolution Structures of CTX-M β-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability
- 1 April 2005
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 348 (2), 349-362
- https://doi.org/10.1016/j.jmb.2005.02.010
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Antibiotic Therapy for Klebsiella pneumoniae Bacteremia: Implications of Production of Extended-Spectrum -LactamasesClinical Infectious Diseases, 2004
- Evolution of an Antibiotic Resistance Enzyme Constrained by Stability and Activity Trade-offsJournal of Molecular Biology, 2002
- An Ultrahigh Resolution Structure of TEM-1 β-Lactamase Suggests a Role for Glu166 as the General Base in AcylationJournal of the American Chemical Society, 2002
- Noncovalent interaction energies in covalent complexes: TEM‐1 β‐lactamase and β‐lactamsProteins-Structure Function and Bioinformatics, 2002
- Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance ThreatClinical Microbiology Reviews, 2001
- Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.Nature Structural & Molecular Biology, 2001
- Contribution of mutant analysis to the understanding of enzyme catalysis: The case of class A β-lactamasesBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1995
- Crystal structure of Escherichia coli TEM1 β‐lactamase at 1.8 Å resolutionProteins-Structure Function and Bioinformatics, 1993
- Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolutionNature, 1992
- β‐lactamase TEM1 of E. coli Crystal structure determination at 2.5 Å resolutionFEBS Letters, 1992