A Toxic Principle from Progestational Endometrium and Placenta

Abstract

Toxic material, which causes death of mice on intraven. injn., can be extracted from progestational endometrium and from placenta of several mammalian spp. Small amts. of material with a similar effect are present in extracts of skeletal muscle. Quantitative estimation of the toxicity of a variety of tissue extracts has been made. Addition of blood or serum rapidly diminishes this toxic property.