Serologische Bestimmung einer immunologisch antideterminierten Zellspezifität bei überempfindlichkeit vom verzögerten Typ

Abstract

Guinea pigs were sensitized with complexes of duck gamma globulin and the homologous rabbit immune serum prepared at antibody excess. These animals showed a delayed type of dermal hypersensitivity if tested 5 to 6 days after sensitization with duck gamma globulin. Suspensions of lymph node cells from such animals removed some antibody from the anti-duck globulin rabbit serum in a specific manner, as demonstrated by hemagglutination with erythrocytes coated with duck globulin.