In the treatment of many malignant lesions certain criteria have been established that leave little or no doubt as to the proper procedure to be followed. This is not true in the treatment of lesions of the gastrointestinal tract, which cause a large percentage of all deaths from malignant lesions. From the therapeutic standpoint, the best attack on all malignant lesions of the gastrointestinal tract is that of surgical extirpation; however, in a certain number of radiosensitive tumors, namely the lymphoblastoma group, radiation therapy becomes an indispensable adjunct to surgery. Lymphosarcoma is the commonest of the tumors arising from the lymphoid structure of the gastrointestinal tract and is the most frequent type of all sarcomas of the digestive system. Though all of the lymphoblastoma group may produce gastrointestinal disturbances by virtue of extrinsic pressure from enlarged retroperitoneal and mesenteric lymph nodes, lymphosarcoma frequently produces intrinsic deformity either as polypoid growths