An excellent symposium on amebiasis, which gives a summary of the present knowledge of the disease, was presented at the 1934 session of the American Medical Association.1This symposium, together with two earlier clinical reports on the results of treatment (Knowles and his associates2in India, and Willner3in China), suggested reviewing experience at the clinic in the past fifteen years with the type of amebiasis that is encountered chiefly among patients from the north temperate zone. There have been numerous reports praising or condemning various drugs, pessimistic and optimistic reports on the possibilities of curing the disease, presentations of results of administering drugs based on insufficient experimental or clinical data, and warnings, possibly unduly fearful, of the danger of using different drugs. An outstanding contribution to the chemotherapy of amebiasis has come from the group headed by Leake, Reed and Anderson. It is from such critical