Isolation of Feline Rotaviruses and Their Relationship to Human and Simian Isolates by Electropherotype and Serotype

Abstract

Rotaviruses were detected by electron microscopy in the faecal specimens of six clinically well cats and virus was subsequently isolated from four of them. Analysis of the RNA of the isolates showed the existence of three electrophoretic types characteristic of the ‘long’ RNA electrophoretic pattern exhibited by rotaviruses. All feline isolates were neutralized only by antiserum to SA11 rotavirus, indicating that these isolates were serotype 3 rotaviruses. Antiserum prepared against a feline strain neutralized all the feline isolates as well as SA11 but showed no neutralizing activity against human isolates of serotype 1, 2 or 4.