Biochemical Targets for Antifungal Azole Derivatives: Hypothesis on the Mode of Action
- 1 January 1985
- book chapter
- Published by Springer Nature
- Vol. 1, 313-351
- https://doi.org/10.1007/978-1-4613-9547-8_12
Abstract
An amazing number of antifungal agents are found within the group of azole-containing compounds. A great number are breakthroughs in anti-fungal therapy in both human and veterinary medicine, and they show excellent activity against phytopathogenic fungi. Structural formulae of some imidazole and triazole derivatives are shown in Figures 12-1 and 12-2.Keywords
This publication has 122 references indexed in Scilit:
- Two species of cytochrome P-450 involved in ergosterol biosynthesis of yeastBiochemical and Biophysical Research Communications, 1983
- Buthiobate: A potent inhibitor for yeast cytochrome P-450 catalyzing 14α-demethylation of lanosterolBiochemical and Biophysical Research Communications, 1983
- Involvement of cytochrome P-450 in Δ22-desaturation in ergosterol biosynthesis of yeastBiochemical and Biophysical Research Communications, 1981
- The 14α—demethylation of lanosterol by a reconstituted cytochrome P-450 system from yeast microsomesBiochemical and Biophysical Research Communications, 1978
- Involvement of cytochrome P-450 and a cyanide-sensitive enzyme in different steps of lanosterol demethylation by yeast microsomesBiochemical and Biophysical Research Communications, 1978
- Interaction of lanosterol to cytochrome P-450 purified from yeast microsomes: Evidence for contribution of cytochrome P-450 to lanosterol metabolismBiochemical and Biophysical Research Communications, 1978
- A highly purified preparation of cytochrome P-450 from microsomes of anaerobically grown yeastBiochemical and Biophysical Research Communications, 1977
- A possible role for cytochrome P-450 during the biosynthesis of zymosterol from lanosterol by Saccharomyces cerevisiaeBiochemical and Biophysical Research Communications, 1974
- Inhibition of ergosterol synthesis in Ustilago maydis by the fungicide triarimolBiochemical and Biophysical Research Communications, 1972
- On the relationship between respiratory activity and lipid composition of the yeast cellBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967