Eosinophilic Meningoencephalitis Caused by Angiostrongyliasis in Thailand
- 1 July 1967
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 16 (4), 454-461
- https://doi.org/10.4269/ajtmh.1967.16.454
Abstract
Summary Autopsy of a 28-year-old Thai woman who died with eosinophilic meningoencephalitis revealed five worms in four of 10 blocks of brain tissue taken for routine microscopic examination. Small areas of disrupted brain tissue containing necrotic-tissue debris and scattered inflammatory cells, mostly histiocytes and neutrophils, were interpreted as tracks of the moving worm. The worms were identified as Angiostrongylus, probably A. cantonensis. Three of the worms apparently dead in the tissues for some days before fixation were encased in a dense exudate and surrounded by a granulomatous reaction, whereas worms with well-preserved tissues and apparently alive at the time of autopsy were free in the tissues. The presence of large numbers of Charcot-Leyden crystals in meninges indicated a massive response by eosinophils to the dead parasites. In addition, vascular congestion was a prominent feature.This publication has 3 references indexed in Scilit:
- Eosinophilic Meningoencephalitis in Thailand: Summary of Nine Cases and Observations on Angiostrongylus Cantonensis as a Causative Agent and Pila Ampullacea as a New Intermediate Host *The American Journal of Tropical Medicine and Hygiene, 1965
- ANGIOSTRONGYLUS CANTONENSIS (NEMATODA: METASTRONGYLIDAE) AS A CAUSATIVE AGENT OF EOSINOPHILIC MENINGOENCEPHALITIS OF MAN IN HAWAII AND TAHITICanadian Journal of Zoology, 1962
- OBSERVATIONS ON AN OUTBREAK OF EOSINOPHILIC MENINGITIS ON TAHITI, FRENCH POLYNESIA1American Journal of Epidemiology, 1961