Inhibition of Leishmania Donovani Amastigote‐To‐Promastigote Transformation By Infected Hamster Spleen Lymphocyte Lysates*
- 31 January 1980
- journal article
- research article
- Published by Wiley in The Journal of Protozoology
- Vol. 27 (1), 87-92
- https://doi.org/10.1111/j.1550-7408.1980.tb04233.x
Abstract
L. donovani amastigote-to-promastigote transformation is inhibited by homogenates of infected hamster liver and spleen. This inhibitory activity is localized in the 100,000 g pellet fraction. Tests with lysates of adherent (macrophages) and nonadherent (lymphocytes) spleen cells indicated that the inhibitory activity resided in the lymphocytes, specifically in the 100,000 g pellet fraction.Keywords
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