GROWTH INHIBITION OF MURINE TUMOR CELLS, IN VITRO, BY PUROMYCIN, [6N]O2'-DIBUTYRYL 3',5'-ADENOSINE MONOPHOSPHATE, OR ADENOSINE
- 1 May 1973
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 57 (2), 397-405
- https://doi.org/10.1083/jcb.57.2.397
Abstract
The cytostatic effects of puromycm, [(6)N]O(2')-dibutyryl 3',5'-adenosine monophosphate, and adenosine on asynchronous and synchronous cultures of the murine mastocytoma, P815Y, have been studied. Cell growth was arrested after a minimum of one further division. A model is proposed for the inhibition of cell division in which the periods of inhibition and growth arrest are separated in time by one cell cycle.Keywords
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