Introduction Definition Report of Cases Personally Observed History of the Subject General Considerations Etiology Genesis of Isolated Dextrocardia Anatomy Cases of Isolated Dextrocardia Studied Anatomically Alone Classification Clinical Observations Based on Cases Reported in the Literature Roentgen Observations Electrocardiographic Observations Diagnosis Prognosis Special Lists of Cases Equivocal Cases Cases Incorrectly Reported as Isolated Dextrocardia Cases of Congenital Dextroversion Situs Inversus of Viscera with Situs Solitus of the Heart Summary INTRODUCTION While cases of total situs inversus have been recognized since antiquity, isolated dextrocardia has been noted only in the past two centuries. Despite its comparative rarity, an extensive casuistic literature exists. This type of dextrocardia merits a comprehensive study, since it involves one of the most complex phases of cardiology. The early contributions to the literature are mainly anatomic, the clinical reports being inadequate in the light of modern cardiologic methods. The roentgenographic and electrocardiographic methods of examination have added