Inhibition of Extracellular Signal–Regulated Kinase Enhances Ischemia/Reoxygenation–Induced Apoptosis in Cultured Cardiac Myocytes and Exaggerates Reperfusion Injury in Isolated Perfused Heart
Top Cited Papers
Open Access
- 31 March 2000
- journal article
- other
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 86 (6), 692-699
- https://doi.org/10.1161/01.res.86.6.692
Abstract
—Three major mammalian mitogen-activated protein kinases, extracellular signal–regulated kinase (ERK), p38, and c-Jun NH2-terminal protein kinase (JNK), have been identified in the cardiomy...Keywords
This publication has 27 references indexed in Scilit:
- TL1, a Novel Tumor Necrosis Factor-like Cytokine, Induces Apoptosis in Endothelial Cells: INVOLVEMENT OF ACTIVATION OF STRESS PROTEIN KINASES (STRESS-ACTIVATED PROTEIN KINASE AND p38 MITOGEN-ACTIVATED PROTEIN KINASE) AND CASPASE-3-LIKE PROTEASEPublished by Elsevier ,1999
- Induction of Apoptosis by SB202190 through Inhibition of p38β Mitogen-activated Protein KinaseJournal of Biological Chemistry, 1998
- Staurosporine-induced Apoptosis in Cardiomyocytes: A Potential Role of Caspase-3Journal of Molecular and Cellular Cardiology, 1998
- Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase PathwaysJournal of Biological Chemistry, 1997
- Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell DeathCell, 1996
- Fibroblast Growth Factor-2 Suppression of Tumor Necrosis Factor α-Mediated Apoptosis Requires Ras and the Activation of Mitogen-activated Protein KinaseJournal of Biological Chemistry, 1996
- Stimulation of c-Jun Kinase and Mitogen-Activated Protein Kinase by Ischemia and Reperfusion in the Perfused Rat HeartBiochemical and Biophysical Research Communications, 1996
- PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in VivoJournal of Biological Chemistry, 1995
- Transformation of Mammalian Cells by Constitutively Active MAP Kinase KinaseScience, 1994
- Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cellsCell, 1994