Abstract
The relaxed length of hydra is increased in the presence of urethane. This suggests a direct effect of urethane on the inner circular myotome layer. Urethane causes the normal transepithelial resting potential to reverse such that the gut becomes negative relative to the external medium. Urethane also causes contraction pulses to become reduced in magnitude. Urethane probably has a direct effect on the hydra myotomes and on the Na transport mechanism.