Effect of Castration upon Susceptibility to MEF1 Poliomyelitis Virus Inoculated Intraperitoneally in Hamsters.
- 1 October 1956
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 93 (1), 111-113
- https://doi.org/10.3181/00379727-93-22679
Abstract
A significant proportion of castrated male hamsters inoculated with MEF1 virus intraperitoneally developed paralytic poliomyelitis, whereas non-castrated controls were completely refractory to the virus by this route. Enhancement of susceptibility observed immediately after castration was reversed during the compensatory stage 2 weeks later. The effect of castration upon susceptibility to experimental poliomyelitis was synergistic with cortisone during the initial stage, but antagonistic during the compensatory stage.Keywords
This publication has 3 references indexed in Scilit:
- Endocrine Factors in Pathogenesis of Experimental Poliomyelitis in Hamsters. Rolde of Iuoculatory and Environmental StressExperimental Biology and Medicine, 1956
- ENDOCRINOLOGICAL ASPECTS OF PATHOGENESIS OF EXPERIMENTAL POLIOMYELITISAnnals of the New York Academy of Sciences, 1955
- RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITISThe Journal of Experimental Medicine, 1954